Epithalon
Epithalon
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Epithalon
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Epitalon, also known as Epithalon or Epithalone, is a synthetic tetrapeptide consisting of four amino acids: alanine, glutamic acid, aspartic acid, and glycine. This peptide has been extensively researched for its potential anti-aging and neuroprotective properties. Epitalon has been shown to regulate melatonin production, influence circadian rhythms, and exhibit antioxidant and anti-inflammatory effects in various studies. Its unique composition and biological activity make it a promising candidate for further research in the fields of longevity, age-related diseases, and neuroprotection. Requires reconstitution before use.
Characteristics
Molecular Formula |
C14H22N4O9 |
CAS |
307297-39-8 |
Molar Mass |
390.34 g/mol |
Chemical Formula |
Ala-Glu-Asp-Gly |
Amino Acid Sequence |
Ala-Glu-Asp-Gly |
Synonyms |
Epithalon, Epithalone, Epitalon, Epithalamin |
Solubility |
Water-soluble |
Organoleptic Profile |
White powder |
Composition |
Synthetic tetrapeptide |
How does Epitalon work?
Epithalon's mechanism of action is believed to involve the regulation of melatonin production and the modulation of circadian rhythms. Melatonin is a hormone that plays a crucial role in sleep-wake cycles, antioxidant defense, and immune function. Studies have shown that Epithalon can stimulate melatonin secretion from the pineal gland, which may contribute to its potential anti-aging and neuroprotective effects.
Additionally, Epithalon has been found to exhibit antioxidant and anti-inflammatory properties. It has been shown to reduce oxidative stress by scavenging free radicals and enhancing the activity of antioxidant enzymes such as superoxide dismutase and catalase. Epithalon's anti-inflammatory effects have been demonstrated in various studies, where it has been shown to downregulate pro-inflammatory cytokines and reduce inflammation in different tissues.
Furthermore, Epithalon has been investigated for its potential effects on telomere length and telomerase activity. Telomeres are protective caps at the ends of chromosomes that shorten with age and are associated with cellular senescence. Some studies suggest that Epithalon may help maintain telomere length and promote telomerase activity, which could contribute to its potential anti-aging properties.
Benefits
- Anti-aging effects: Epithalon has been studied for its potential to prolong lifespan and reduce age-related degenerative changes in various animal models.
- Neuroprotection: Several studies have demonstrated Epithalon's neuroprotective properties, suggesting its potential in preventing or mitigating age-related cognitive decline and neurodegenerative diseases.
- Antioxidant and anti-inflammatory effects: Epithalon has been shown to reduce oxidative stress and inflammation, which are key factors in the aging process and the development of age-related diseases.
- Regulation of circadian rhythms: By stimulating melatonin production, Ephitalon may help regulate sleep-wake cycles and improve sleep quality, which are essential for overall health and well-being.
- Potential effects on telomere length and telomerase activity: Some studies suggest that Epithalon may help maintain telomere length and promote telomerase activity, which could contribute to its potential anti-aging properties.
Side Effects
Epithalon is generally considered safe and well-tolerated, with no significant side effects reported in most studies. However, as with any substance, individual responses may vary, and further research is needed to fully understand its long-term safety profile. It is essential to consult with a qualified healthcare professional before considering the use of Epithalon or any other peptide for research purposes.

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